As the main protein found in the body, collagen plays a vital role in a healthy musculoskeletal system. forming the structural component in all our connective tissues including bones, cartilage, joints, tendons, ligaments and muscles, collagen supports key physical functions such as movement, posture and stability.

As we age, bone resorption begins to exceed bone formation. We can help to preserve our bone health with regular exercise and a balanced diet that includes the right nutrients : along with vitamin D and calcium, protein is essential. CARTENIUM® Bovine Hydrolyzed Collagen is efficiently digested (<90%) and absorbed into the blood stream in form of small peptides within one hour. It helps balance bone formation and bone breakdown by actively stimulating bone building metabolism (proliferation, differentiation and mineralization of osteoblasts) and by slowing down the activity of bone-degrading cells (differentiation and function of osteoclasts).

 

THE SCIENCE BEHIND CARTENIUM®

Developed by GELITA, FORTIGEL® is an innovative ingredient for the regeneration of joint cartilage. Collagenous protein makes up nearly 70% of cartilage mass. Optimized specific collagen peptides of FORTIGEL® have been proven to activate the growth of new cartilage by stimulating cells helping to ease joint discomfort and make the joints smooth and mobile. By keeping people physically active and mobile, FORTIGEL® can improve quality of life.

The special GELITA manufacturing process on a permanent high quality standard is responsible for the proven efficacy of Bioactive Collagen Peptides® on different human tissues regardless collagen type I or II would have been used as raw material. 

CARTENIUM® has clinically demonstrated its role in the musculoskeletal health.

CARTENIUM®’s active ingredient bovin hydrolyzed collagen is backed by numerous scientific studies showing its important health benefits. This clinical study was done on a group and was carried on 30 healthy male subjects from 50 to 70 y.o, during spring and for 12 weeks. The objective was to evaluate the musculoskeletal potential of oral intake of CARTENIUM® (10 000 mg of bovine collagen peptides).

SYNTHESIS OF CARTILAGE
BONE STRENGTH
CARTILAGE DEGRADATION
BONE STRENGTH
JOINT INFLAMMATION
BONE MINERAL DENSITY

CARTENIUM® has clinically demonstrated its role in the musculoskeletal health.

SYNTHESIS OF CARTILAGE

Effect of different concentrations of Peptan on the gene expression of extracellular matrix components (aggrecan and collagen Type II) in chrondrocytes.
Internal study unpublished data 2011

BONE STRENGTH

Menopause was induced by ovariectomy (Ovx) inmice and the animals were supplemented with Peptan or a control for twelve weeks. The ultimate bon strength was determined by the 3-point bending test.

Guillerminet, 2010, 2012

CARTILAGE DEGRADATION

Osteoarthritis (OA) was induced by surgery in mice that received Peptan at two different dosages or a control twelve weeks after OA induction. Histology of the knee joints was performed and the area of the (tibia) cartilage was quantified.
Dar , 2016

JOINT INFLAMMATION
Three weeks after OA induction the joint synovium was analyzed for the gene expression of inflammatory markers (TNF). Dar, 2016
BONE MINERAL DENSITY

Menopause was induced by ovariectomy (Ovx) in mice and the animals were supplemented with Peptan or a control for twelve weeks. Bone mineral density was measured by DEXA.

Guillerminet, 2010, 2012

CARTENIUM®’s active ingredient bovin hydrolyzed collagen is backed by numerous scientific studies showing its important health benefits. This clinical study was done on a group and was carried on 30 healthy male subjects from 50 to 70 y.o, during spring and for 12 weeks. The objective was to evaluate the musculoskeletal potential of oral intake of CARTENIUM® (10 000 mg of bovine collagen peptides).

 

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